A fourth dose of mRNA-based vaccine may be warranted in some kidney transplant recipients

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Case series published in Annual report of internal medicine We found that a fourth dose of the mRNA-based vaccine resulted in a satisfactory antibody response to some kidney transplant recipients who did not respond appropriately after the previous three doses. These findings support the use of a fourth vaccination for such patients.

Researchers at Strasbourg University Hospital have studied 92 liver Transplant Recipients of three independent university hospitals in France have shown that the fourth dose of the mRNA-based anti-SARS-CoV-2 vaccine showed a weak serological response after the third dose of the kidney transplant recipient’s anti-spikes. Investigate whether to increase IgG titer.

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Patients whose anti-spiked IgG titer was less than 143 BAU / mL 1 month after the 3rd dose of the vaccine were given the 4th mRNA vaccine and the anti-spike IgG titer was measured 2-6 weeks later. I did it. The researchers found no safety concerns with the fourth dose and noted that after a median of 29 days, the median anti-spiked IgG levels were significantly increased. vaccination There may be good reasons for these patients.

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A third dose of COVID-19 vaccine may stimulate the transplant recipient’s response


For more information:
Antibody Response to Kidney Transplant Recipient’s Fourth Messenger RNA COVID-19 Vaccination: Case Series, Annual report of internal medicine (2022). DOI: 10.7326 / L21-0598

Quote: Https: //medicalxpress.com/news/2022-01-fourth-dose-mrna-based-in some kidney transplant recipients (January 10, 2022) obtained on January 10, 2022 , A fourth dose of mRNA-based vaccine may be guaranteed. Vaccine-warranted.html

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A fourth dose of mRNA-based vaccine may be warranted in some kidney transplant recipients Source link A fourth dose of mRNA-based vaccine may be warranted in some kidney transplant recipients